A combination FPLC/HPLC for the purification of proteins and synthetic binding partners
A combination FPLC/HPLC for the purification of proteins and synthetic binding partners
批准号:
360250-2008
负责人:
Wulff, Jeremy
金额:
$6.57万
依托单位:
依托单位国家:
加拿大
项目类别:
Research Tools and Instruments - Category 1 (<$150,000)
财政年份:
2007
资助国家:
加拿大
项目状态:
已结题
起止时间:
2007-01-01 至 2008-12-31
中文摘要
我的团队研究开发用于控制蛋白质-蛋白质相互作用的新的合成分子,关键取决于我们提纯感兴趣的蛋白质和旨在影响其功能的小分子的能力。这项建议寻求资金,以建立快速蛋白质液相色谱(FPLC)/高效液相色谱(HPLC)的组合系统,用于纯化各种大小的分子(包括蛋白质等生物分子)。这台设备是我的团队努力开发蛋白质-蛋白质相互作用的新型化学调节剂的重要组成部分,其长期目标是设计出治疗癌症、艾滋病毒/艾滋病和其他疾病的根本性新药。
英文摘要
My group's research on developing new synthetic molecules for the control of protein-protein interactions depends critically upon our ability to purify both proteins of interest and the small molecules that are intended to affect their function.This proposal seeks funds for a combination Fast Protein Liquid Chromatography (FPLC) / High Performance Liquid Chromatography (HPLC) system to be used for the purification of molecules of all sizes (including biological molecules like proteins). This equipment is an essential part of my group's efforts to develop novel chemial modulators of protein-protein interactions, with a long-term goal of engineering fundamentally new medicines for the treatment of cancer, HIV/AIDS, and other diseases.
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批准号:RGPIN-2021-02560
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.5万
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依托单位:
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依托单位:
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批准号:RGPIN-2021-02560
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.5万
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依托单位:
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资助金额:$3.35万
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资助金额:$7.29万
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依托单位:
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批准号:CRC-2016-00290
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依托单位:
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批准号:522165-2017
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资助金额:$3.35万
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财政年份:2017
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依托单位:
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批准号:CRC-2016-00290
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财政年份:2017
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批准号:1000226685-2011
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资助金额:$5.46万
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依托单位:
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资助金额:$1.82万
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财政年份:2016
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依托单位:
High-level characterization of the effects of de-icing salts on polymer composite insulator shed hydrophobicity and monomer leakage
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批准号:500759-2016
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财政年份:2016
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依托单位:
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