Regulation of ERK driven cell proliferation by the actin cytoskeleton

肌动蛋白细胞骨架对 ERK 驱动细胞增殖的调节

• 批准号: nhmrc : 1100202
• 负责人: A/Pr Till Boecking
• 金额: $ 63.37万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/regulation-erk-driven-actin-cytoskeleton/662498
• 关键词: Regulation; ERK; driven; cell; proliferation

The cells in your body respond to external signals and control their proliferation by transmitting signals from one part of the cell to another. This has usually been thought to involve the movement of signals through a liquid medium without the involvement of any machinery to control the movement. The project aims to test the role of the architecture of the cells in physically moving a growth signal from one place to another. We think that the architecture involved plays a key role in cancer.

你体内的细胞对外部信号作出反应，并通过将信号从细胞的一个部分传递到另一个部分来控制它们的增殖。这通常被认为涉及信号通过液体介质的运动，而不涉及任何机械来控制运动。该项目旨在测试细胞结构在物理上将生长信号从一个地方移动到另一个地方的作用。我们认为所涉及的结构在癌症中起着关键作用。