Thermoanalytical equipment (DSC and TGA) for investigation of composition and physicochemichal properties of novel host-guest materials

用于研究新型主客体材料的组成和物理化学性质的热分析设备（DSC 和 TGA）

• 批准号: 360330-2008
• 负责人: Soldatov, Dmitriy
• 金额: $ 10.66万
• 依托单位: University of Guelph
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments - Category 1 (<$150,000)
• 财政年份: 2007
• 资助国家: 加拿大
• 起止时间: 2007-01-01 至 2008-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=365605
• 关键词: Thermoanalytical; equipment; DSC; TGA; investigation

The requested set of state-of-the-art thermoanalytical instruments, Q2000 Modulated Differential Scanning Calorimeter (DSC) and Q5000 IR Thermogravimetry Analyzer (TGA), will be used as a primary tool for the characterization of new materials developed in our emerging group. The materials to be developed are inclusion or coordination compounds with a volatile component (guest or ligand). The obtained information will be used to obtain essential information on the stoichiometry and stability of these delicate, short-lived materials. The results will define the properties, stabilities and behavior (including the way of handling) for each particular material and the sequence of further experiments needed to adequately describe it and evaluate its usefulness for various potential applications: gas storage/separation, encapsulation of molecular species, preservation/delivery of pharmaceuticals, odors and flavors.   Our group will exploit two novel types of hosts: (1) hydrophobic lower peptides and (2) ladder-and-platform low-dimensional coordination oligomers/polymers. We will be one of very few groups in the world to extensively use the methods of thermal analysis in combination with synthetic and X-ray diffraction studies, and the very first research group to identify thermal properties of bulk inclusion materials based on peptides.   The set of two instruments will be controlled from a single computer to allow the collection and comparison of complementary data: the thermodynamic characteristics of phase transitions (DSC) and the stoichiometry of the corresponding reactions (TGA). In addition, the equipment will be used to develop further complex experiments such as the determination of sorption isotherms and phase diagrams.   The requested equipment is critical to start our research as it will be the only characterization facility available in the lab. The equipment will be utilized on a daily basis by all students and fellows working on the project (Discovery Grant proposal) and will both develop their professional, practical skills and give them insight into fundamental knowledge regarding heterogeneous equilibria and thermodynamics.

所要求的一套最先进的热分析仪器，Q2000调制差示扫描量热仪（DSC）和Q5000红外热重分析仪（TGA），将被用作我们新兴团队开发的新材料表征的主要工具。待开发的材料是具有挥发性组分（客体或配体）的包合物或配位化合物。所获得的信息将用于获得有关这些脆弱的短寿命材料的化学计量和稳定性的基本信息。结果将定义每种特定材料的性质，稳定性和行为（包括处理方式）以及进一步实验的顺序，以充分描述它并评估其在各种潜在应用中的有用性：气体储存/分离，分子物质的封装，药物，气味和风味的保存/递送。 我们的团队将开发两种新型的宿主：（1）疏水性低分子肽和（2）梯-平台低维配位低聚物/聚合物。我们将是世界上为数不多的几个广泛使用热分析方法与合成和X射线衍射研究相结合的研究小组之一，也是第一个确定基于肽的散装包合物材料的热性质的研究小组。 这套两台仪器将由一台计算机控制，以收集和比较互补数据：相变的热力学特征（DSC）和相应反应的化学计量（TGA）。此外，该设备还将用于开发进一步的复杂实验，如确定吸附等温线和相图。 所要求的设备对于开始我们的研究至关重要，因为它将是实验室中唯一可用的表征设施。该设备将每天使用的所有学生和研究员的项目工作（发现补助金提案），并将发展他们的专业，实践技能，让他们深入了解有关非均相平衡和热力学的基础知识。