Regulation of mammalian heart regeneration by the miR-15 family.
Regulation of mammalian heart regeneration by the miR-15 family.
批准号:
nhmrc : 1033815
负责人:
A/Pr Enzo Porrello
金额:
$29.06万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2012
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2012-01-01 至 2014-12-31
中文摘要
成年人心脏病发作后无法再生是发达国家心脏病负担的主要原因。我们最近发现,在出生后的短暂时间内,新生心脏可以在受伤后完全再生。了解心脏如何以及为什么在出生后不久就失去了这种非凡的再生能力,可能是开发心脏再生疗法的关键。
英文摘要
The inability of the adult heart to regenerate following a heart attack is a major contributor to the burden of heart disease in the developed world. We have recently discovered that, for a brief period after birth, the newborn heart can completely regenerate itself following injury. Understanding how and why the heart loses this remarkable capacity for regeneration shortly after birth may hold the key for developing cardiac regenerative therapies.
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会议论文
Targeted direct reprogramming of adult cardiac fibroblasts to functional cardiomyocytes
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批准号:nhmrc : GNT1107261
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项目类别:Project Grants
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资助金额:$61.85万
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财政年份:2016
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负责人:A/Pr Enzo Porrello
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依托单位:
An RNA-based strategy for heart regeneration.
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批准号:nhmrc : GNT1108127
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项目类别:Career Development Fellowships
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资助金额:$41.92万
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财政年份:2016
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负责人:A/Pr Enzo Porrello
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依托单位:
An RNA-based strategy for heart regeneration.
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批准号:nhmrc : 1108127
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项目类别:Career Development Fellowships
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资助金额:$28.84万
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财政年份:2016
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负责人:A/Pr Enzo Porrello
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依托单位:
Targeted direct reprogramming of adult cardiac fibroblasts to functional cardiomyocytes
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批准号:nhmrc : 1107261
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项目类别:Project Grants
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资助金额:$42.35万
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财政年份:2016
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负责人:A/Pr Enzo Porrello
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依托单位:
Regulation of endogenous heart regeneration by an anti-fibrotic microRNA.
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批准号:nhmrc : GNT1080505
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项目类别:Project Grants
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资助金额:$42.71万
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财政年份:2015
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负责人:A/Pr Enzo Porrello
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依托单位:
Regulation of heart development and regeneration by DNA methylation.
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批准号:nhmrc : 1080507
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项目类别:Project Grants
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资助金额:$36.85万
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财政年份:2015
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负责人:A/Pr Enzo Porrello
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依托单位:
Regulation of endogenous heart regeneration by an anti-fibrotic microRNA.
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批准号:nhmrc : 1080505
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项目类别:Project Grants
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资助金额:$29.4万
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财政年份:2015
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负责人:A/Pr Enzo Porrello
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依托单位:
Regulation of heart development and regeneration by DNA methylation.
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批准号:nhmrc : GNT1080507
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项目类别:Project Grants
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资助金额:$53.56万
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财政年份:2015
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负责人:A/Pr Enzo Porrello
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依托单位:
Control of cardiac growth and development by miR-195.
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批准号:nhmrc : 635530
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项目类别:Early Career Fellowships
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资助金额:$23.68万
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财政年份:2010
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负责人:A/Pr Enzo Porrello
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依托单位:
国内基金
海外基金
镉激活神经细胞mTOR通路诱导凋亡及雷帕霉素靶向调控抗凋亡分子机理
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批准号:30971486
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项目类别:面上项目
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资助金额:31.0万元
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批准年份:2009
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负责人:陈龙
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依托单位: