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An RNA-based strategy for heart regeneration.

An RNA-based strategy for heart regeneration.
基于 RNA 的心脏再生策略。
批准号:
nhmrc : GNT1108127
负责人:
A/Pr Enzo Porrello
金额:
$41.92万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Career Development Fellowships
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-01-01 至 --

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中文摘要
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英文摘要
The adult heart has an extremely limited capacity for regeneration. In contrast, I recently discovered that the newborn heart can completely regenerate following a heart attack. How and why the heart loses this regenerative capacity after birth is not known. This Fellowship aims to unravel the genetic circuits that govern cardiac regenerative capacity. The proposed research program will develop novel therapies for heart regeneration through molecular targeting of regulatory RNA molecules.
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Targeted direct reprogramming of adult cardiac fibroblasts to functional cardiomyocytes
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An RNA-based strategy for heart regeneration.
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