Regulation of heart development and regeneration by DNA methylation.
Regulation of heart development and regeneration by DNA methylation.
批准号:
nhmrc : 1080507
负责人:
A/Pr Enzo Porrello
金额:
$36.85万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2015
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2015-01-01 至 2018-12-31
中文摘要
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英文摘要
The adult mammalian heart has an extremely limited capacity for regeneration following a heart attack, which is in stark contrast to the robust regenerative capacity of the newborn heart. How and why mammals lose their ability to regenerate heart tissue after birth is not well understood. We propose a new approach to unravel the complex mechanisms that control gene expression during heart development in rodents and humans, which could provide new therapeutic avenues for heart regeneration.
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Targeted direct reprogramming of adult cardiac fibroblasts to functional cardiomyocytes
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资助金额:$61.85万
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财政年份:2016
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依托单位:
An RNA-based strategy for heart regeneration.
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An RNA-based strategy for heart regeneration.
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批准号:nhmrc : 1108127
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项目类别:Career Development Fellowships
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依托单位:
Targeted direct reprogramming of adult cardiac fibroblasts to functional cardiomyocytes
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批准号:nhmrc : 1107261
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项目类别:Project Grants
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财政年份:2016
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依托单位:
Regulation of endogenous heart regeneration by an anti-fibrotic microRNA.
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批准号:nhmrc : GNT1080505
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项目类别:Project Grants
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资助金额:$42.71万
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财政年份:2015
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负责人:A/Pr Enzo Porrello
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依托单位:
Regulation of endogenous heart regeneration by an anti-fibrotic microRNA.
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批准号:nhmrc : 1080505
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项目类别:Project Grants
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资助金额:$29.4万
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财政年份:2015
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负责人:A/Pr Enzo Porrello
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依托单位:
Regulation of heart development and regeneration by DNA methylation.
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批准号:nhmrc : GNT1080507
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项目类别:Project Grants
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资助金额:$53.56万
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财政年份:2015
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负责人:A/Pr Enzo Porrello
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依托单位:
Regulation of mammalian heart regeneration by the miR-15 family.
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批准号:nhmrc : 1033815
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项目类别:Project Grants
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资助金额:$29.06万
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财政年份:2012
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负责人:A/Pr Enzo Porrello
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依托单位:
Control of cardiac growth and development by miR-195.
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项目类别:Early Career Fellowships
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资助金额:$23.68万
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财政年份:2010
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负责人:A/Pr Enzo Porrello
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依托单位:
国内基金
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