To purchase an ultra low temperature chest freezer (-80ºC)

这项设备申请是为了更换已有17年历史的超低温冰柜，这是我们研究基础设施的重要组成部分。此外，新的超低温(-80摄氏度)冰柜也将有二氧化碳备份系统，因此如果出现冰柜故障或断电(自从我们搬进新大楼以来已经有两个)，温度将保持不变。旧冰柜出现故障是一个主要问题，因为无论白天或晚上，人们都必须去实验室，找到另一个有空间的-80摄氏度冰柜。并转移冰柜的全部内容物，以避免宝贵试剂的灾难性损失。-80oC冰柜为我们多年来积累的重要生物研究材料和独特的科学样本提供了必要的存储。这些生物样本需要保持在-60oC到-80oC之间，才能长期存活。生物样本是实验室进行研究所必需的，实验室运行的时间越长，材料的库存就越广泛和重要。我们已经进行了17年的研究，收集了独特的、不可替代的研究工具，我们需要一个安全可靠的冰柜来储存这些物品。我们需要一个安全可靠的冰柜来储存这些物品。为这一关键项目提供资金将使我们由NSERC资助的旨在了解CD44在细胞黏附和迁移中的作用的研究计划能够持续下去。这项关于细胞停止和移动的基础研究在细胞生物学中具有根本的重要性。在分子水平上了解你体内的细胞如何运动以及它们何时粘连提供了必要和基本的构建块，这将允许未来开发旨在促进的新生物技术，模仿或防止细胞移动或细胞黏附。通过投资于这项基础研究，加拿大人正在确保科学发现和进步为子孙后代继续下去。

This equipment request is to replace a 17 year old ultra low temperature freezer that is an essential component of our research infrastructure.  The new ultra low temperature (-80oC) freezer will also have a carbon dioxide back up system, so that if there is a freezer failure or power cut (there has been two already since we move into our new building!), the temperature will be maintained.  Break downs with old freezers are a major concern, as no matter what time of day or night, one has to go to the lab, find another -80oC freezer that has space, and transfer the entire contents of the freezer in order to avoid a catastrophic loss of valuable reagents.  The -80oC freezer provides essential storage for important biological research materials and unique scientific samples that we have accumulated over the years. These biological samples need to be kept between -60oC and -80oC for their long-term viability. The biological samples are necessary for the lab to do its research and the longer the lab has been in operation, the more extensive and important the inventory of materials.  We have been pursuing our research for 17 years and have collected a unique and irreplaceable collection of research tools, samples and reagents that are also available to the world-wide research community upon request.  We need a safe and reliable freezer to store these items.  Funding of this critical item will allow the sustainability of our NSERC funded research program that is aimed at understanding the role of CD44 in cell adhesion and migration.  This basic research into what makes a cell stop and what makes them go is of fundamental importance in cell biology.  Understanding at the molecular level how the cells in your body move and when they stick provides the essential and basic building blocks that will allow for the future development of new biotechnologies designed to facilitate, mimic or prevent cell movement or cell adhesion.  By investing in this basic research, Canadians are ensuring the continuation of scientific discovery and progress for future generations.