Respiratory phenotyping for new targeted approaches to treat sleep apnoea

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>9% of Australians have obstructive sleep apnoea (OSA). OSA has several causes. Untreated OSA is associated with major health consequences. <50% of OSA patients tolerate the main therapy, continuous positive airway pressure. New treatments are urgently required. This proposal aims to use & develop novel approaches to identify the causes of OSA on a per patient basis, improve current therapies & test if new targeted therapies can be used to treat OSA in appropriately selected patients.