The role of B7 family members in the generation of immunological memory

B7家族成员在免疫记忆生成中的作用

• 批准号: nhmrc : 481374
• 负责人: Dr Kim Jacobson
• 金额: $ 29.16万
• 依托单位: The Walter and Eliza Hall Institute of Medical Research
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/role-b7-family-immunological-memory/115402
• 关键词: role; B7; family; members; generation

Memory immune cells remember antigens that have previously induced an immune response. Therefore, they can react quickly and rigorously to stop subsequent infections. This project will study the role of the B7 family of proteins in communication between memory cells and other cells of the immune system to produce lifetime protection against foreign antigens. Understanding these processes will assist in creating more effective vaccines and treatments for immunodeficient or autoimmune patients.

记忆免疫细胞会记住先前引起免疫反应的抗原。因此，他们可以迅速而严格地做出反应，阻止随后的感染。该项目将研究B7蛋白家族在记忆细胞和免疫系统其他细胞之间的通讯中所起的作用，从而产生对外来抗原的终身保护。了解这些过程将有助于为免疫缺陷或自身免疫患者创造更有效的疫苗和治疗方法。