The role of fatty acid metabolism in renin secretion

脂肪酸代谢在肾素分泌中的作用

• 批准号: nhmrc : 603810
• 负责人: Prof David Power
• 金额: $ 38.83万
• 依托单位: Institute for Breathing and Sleep
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/role-fatty-acid-renin-secretion/98492
• 关键词: role; fatty; acid; metabolism; renin

People who are overweight often have high blood pressure. This project aims to find out why. By showing that the kidneys, which control blood pressure, use fat as an important controller of their function, we may be able to work out ways to modify the relationship between obesity and high blood pressure. The project wil be performed in genetically modified mice, but we expect that the findings will be applicable to humans.

超重的人通常患有高血压。该项目旨在找出原因。通过证明控制血压的肾脏利用脂肪作为其功能的重要控制者，我们也许能够找到改变肥胖和高血压之间关系的方法。该项目将在转基因小鼠中进行，但我们预计研究结果将适用于人类。