The role of H2-Q10 in liver immunity

就免疫反应而言，肝脏是一个重要器官。由于它暴露于许多抗原，需要保持某种形式的免疫耐受。这确保了不会发生明显的免疫反应，而免疫反应会损害肝脏。产生耐受性的一种方法是通过调节主要组织相容性复合体（MHC）分子使杀伤细胞沉默。该项目将探索仅在肝脏中表达的MHC的可溶性形式的作用。

The liver is an important organ in terms of immune responses. Owing to its exposure to many antigens, it is required to maintain a form of immune tolerance. This ensures that overt immune responses which would damage the liver do not occur. One means by which tolerance occurs is through silencing killer cells through the regulation of molecules of Major Histocompatibility Complex (MHC). This project will explore the role of a soluble form of MHC which is expressed only in the liver.