The role of microglia in early diabetic retinopathy

小胶质细胞在早期糖尿病视网膜病变中的作用

• 批准号: nhmrc : 1138509
• 负责人: A/Pr Bang Bui
• 金额: $ 45万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/role-microglia-early-diabetic-retinopathy/1318771
• 关键词: role; microglia; early; diabetic; retinopathy

Diabetic retinopathy is one of the most feared complications of diabetes. This project will examine the role that retinal immune cells called microglia have in causing early changes in the vasculature. We will examine whether diabetes changes the way neurons communicate with blood vessels, opening up a possible treatment target that could prevent the progression to more advanced disease.

糖尿病视网膜病变是糖尿病最可怕的并发症之一。这个项目将研究称为小胶质细胞的视网膜免疫细胞在导致血管系统早期变化中所起的作用。我们将研究糖尿病是否改变了神经元与血管沟通的方式，开辟了一个可能的治疗目标，可以防止进展为更晚期的疾病。