Dehydration of biological materials with radiant microwave energy under vacuum

真空下辐射微波能对生物材料进行脱水

• 批准号: 36615-2008
• 负责人: Durance, Timothy
• 金额: $ 2.62万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2008
• 资助国家: 加拿大
• 起止时间: 2008-01-01 至 2009-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=390177
• 关键词: Dehydration; biological; materials; radiant; microwave

Radiant Energy Vacuum (REV) is technique for drying heat-sensitive materials very quickly but at low temperatures so as not to damage biological activity. Essentially, vacuum is employed to lower the boiling point of water to just above the freezing point, then microwaves are applyed to quickly evaporate the water without raising the temperature to damaging levels. Although based on principles established by others in the past, my research group has spent the last 10 years developing REV into a practical drying technology. REV is currently protected by about a dozen patents, most of them owned by The University of British Columbia. These patents have been licensed to a Canadian company whose goal is to commercialize the technology. Today REV is used for drying a few high-value food products such as berries and mushrooms. We have shown that it is able to dry bacteria without killing the cells, as well as to dry several drugs, antibiotics, enzymes and antibodies with little or no damage. We hope to further prove the usefulness of the technology for drying and stabilizing vaccines, probiotic bacteria, and natural antimicrobial agents, as well as some innovative medical materials.

辐射能真空（REV）是一种快速干燥热敏材料的技术，但在低温下，以免破坏生物活性。从本质上讲，真空是用来降低水的沸点略高于凝固点，然后微波是applied迅速蒸发的水，而不会提高温度到破坏性的水平。虽然基于过去其他人建立的原则，但我的研究小组在过去的10年里将REV发展成为一种实用的干燥技术。REV目前受到大约十几项专利的保护，其中大部分由不列颠哥伦比亚省大学拥有。这些专利已授权给一家加拿大公司，该公司的目标是将该技术商业化。今天，REV用于干燥一些高价值的食品，如浆果和蘑菇。我们已经证明，它能够在不杀死细胞的情况下干燥细菌，以及干燥几种药物，抗生素，酶和抗体，几乎没有或没有损害。我们希望进一步证明该技术在干燥和稳定疫苗、益生菌和天然抗菌剂以及一些创新医疗材料方面的实用性。