Significance of microparticles in the pathogenesis of liver ischemia reperfusion injury
Significance of microparticles in the pathogenesis of liver ischemia reperfusion injury
批准号:
nhmrc : 1008958
负责人:
Prof Geoffrey Farrell
金额:
$42.94万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2011
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2011-01-01 至 2013-12-31
中文摘要
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英文摘要
The overall aim of the project is to investigate the significance of microparticles in liver ischemia reperfusion injury (IRI). IRI causes damage to donor livers stored in preparation for liver transplantation. We postulate that microparticles released from the liver are critical in this form of injury. The expected outcomes are novel insights into liver IRI with the aim of developing new approaches to prevent liver damage during liver surgery, transplantation and shock.
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Liver lipotoxicity and NASH: mechanistic roles of free cholesterol, saturated FFA, JNK1 and TLR4
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批准号:nhmrc : GNT1084136
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项目类别:Project Grants
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资助金额:$41.64万
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财政年份:2015
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负责人:Prof Geoffrey Farrell
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依托单位:
Liver lipotoxicity and NASH: mechanistic roles of free cholesterol, saturated FFA, JNK1 and TLR4
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批准号:nhmrc : 1084136
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项目类别:Project Grants
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资助金额:$28.65万
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财政年份:2015
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负责人:Prof Geoffrey Farrell
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依托单位:
Microparticles in NASH: origins, pathogenic roles, and biomarker of disease activity
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批准号:nhmrc : 1044288
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项目类别:Project Grants
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资助金额:$36.05万
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财政年份:2013
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负责人:Prof Geoffrey Farrell
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依托单位:
Protecting fatty livers from hepatic ischemia-reperfusion injury in liver surgery and transplantation
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批准号:nhmrc : 1010082
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项目类别:Project Grants
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资助金额:$41.67万
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财政年份:2011
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负责人:Prof Geoffrey Farrell
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依托单位:
MECHANISTIC ROLE OF CHOLESTEROL IN NON-ALCOHOLIC STEATOHEPATITIS
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批准号:nhmrc : 585411
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项目类别:NHMRC Project Grants
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资助金额:$35.58万
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财政年份:2010
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负责人:Prof Geoffrey Farrell
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依托单位:
MOLECULAR AND CELLULAR PATHOGENESIS OF HUMAN LIVER DISEASE
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批准号:nhmrc : 358398
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项目类别:Programs
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资助金额:$328.62万
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财政年份:2005
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负责人:Prof Geoffrey Farrell
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依托单位:
Preconditioning: the molecular basis for protection from hepatic ischemia-reperfusion injury
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批准号:nhmrc : 211137
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项目类别:NHMRC Project Grants
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资助金额:$27.14万
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财政年份:2002
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负责人:Prof Geoffrey Farrell
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依托单位:
ALCOHOL AND IMPAIRED LIVER REGENERATION: EFFECTS ON MITOGENIC SIGNALING PATHWAYS
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批准号:nhmrc : 107293
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项目类别:NHMRC Project Grants
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资助金额:$24.36万
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财政年份:2000
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负责人:Prof Geoffrey Farrell
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依托单位:
The mechanism of flucloxacillin hepatotoxicity
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批准号:nhmrc : 980063
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项目类别:NHMRC Project Grants
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资助金额:$11.33万
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财政年份:1998
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负责人:Prof Geoffrey Farrell
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依托单位:
Alcohol and calcium_signalling
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批准号:nhmrc : 970733
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项目类别:NHMRC Project Grants
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资助金额:$20.81万
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财政年份:1997
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负责人:Prof Geoffrey Farrell
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依托单位:
How anticancer drugs damage the liver
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批准号:nhmrc : 960917
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项目类别:NHMRC Project Grants
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资助金额:$8.63万
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财政年份:1996
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负责人:Prof Geoffrey Farrell
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依托单位:
How do drugs cause hepatitis and jaundice
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批准号:nhmrc : 940027
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项目类别:NHMRC Project Grants
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资助金额:$16.74万
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财政年份:1994
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负责人:Prof Geoffrey Farrell
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依托单位:
Liver enzymes and obstructed bile flow
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批准号:nhmrc : 920341
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项目类别:NHMRC Project Grants
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资助金额:$8.59万
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财政年份:1992
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负责人:Prof Geoffrey Farrell
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依托单位:
Alcohol and liver regeneration.
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批准号:nhmrc : 910837
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项目类别:NHMRC Project Grants
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资助金额:$7.25万
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财政年份:1991
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负责人:Prof Geoffrey Farrell
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依托单位:
Interferon alters the enzymes which break down drugs in the liver
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批准号:nhmrc : 910805
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项目类别:NHMRC Project Grants
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资助金额:$15.63万
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财政年份:1991
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负责人:Prof Geoffrey Farrell
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依托单位:
Understanding how anaesthetic gases can cause liver dam age in animals.
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批准号:nhmrc : 910840
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项目类别:NHMRC Project Grants
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资助金额:$9.37万
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财政年份:1991
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负责人:Prof Geoffrey Farrell
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依托单位:
Nikon inverted microscope diaphot
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批准号:nhmrc : 911206
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项目类别:NHMRC Infrastructure Grants
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资助金额:$1.91万
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财政年份:1991
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负责人:Prof Geoffrey Farrell
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依托单位:
Changes in special enzymes for drug breakdown in cirrho sis of the liver
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批准号:nhmrc : 900764
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项目类别:NHMRC Project Grants
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资助金额:$12.48万
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财政年份:1990
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负责人:Prof Geoffrey Farrell
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依托单位:
Changes in liver blood supply and sex hormone breakdown in rats and patients
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批准号:nhmrc : 890391
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项目类别:NHMRC Project Grants
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资助金额:$5.7万
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财政年份:1989
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负责人:Prof Geoffrey Farrell
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依托单位:
Interferon blocks excretion of other drugs
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批准号:nhmrc : 880220
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项目类别:NHMRC Project Grants
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资助金额:$5.95万
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财政年份:1988
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负责人:Prof Geoffrey Farrell
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依托单位:
国内基金
海外基金
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批准号:81470560
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项目类别:面上项目
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资助金额:73.0万元
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批准年份:2014
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负责人:钟明
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依托单位:
微粒(Microparticles)在狼疮肾炎发病中的作用及其潜在信号通路的研究
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批准号:81202348
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项目类别:青年科学基金项目
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资助金额:23.0万元
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批准年份:2012
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负责人:何春燕
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依托单位: