Replacement tabletop ultracentrifuge
Replacement tabletop ultracentrifuge
批准号:
359762-2008
负责人:
Trimble, William
金额:
$5.81万
依托单位:
依托单位国家:
加拿大
项目类别:
Research Tools and Instruments - Category 1 (<$150,000)
财政年份:
2008
资助国家:
加拿大
项目状态:
已结题
起止时间:
2008-01-01 至 2009-12-31
中文摘要
超离心涉及通过非常高的离心力分离不同尺寸的颗粒。 这项技术是现代生物学的基础,需要一台能够实现如此高力量的专用机器。 细胞生物学和生物化学领域的大多数实验室常规使用这种技术,这些机器的需求量非常大。 台式超离心分离机专为分离小样品而设计,可实现非常高的分离力。 我们以前有一个桌面超级电脑,但这台机器已经超过15年了,现在已经过时了。 在其最后一次故障期间,服务代表表示零件不再可用于维修,需要更换。 我们的调查小组目前正在前往其他建筑物进行超浓缩,但与此相关的问题不仅是旅行时间和在其他人的设备上预订时间的困难。 主要问题是,如果分离后不立即使用,样品可能会降解,在某些情况下,分离的材料可能在运输过程中重新混合。因此,目前的申请是寻找一种可以安置在我们实验室中心空间的机器的替代品。
英文摘要
Ultracentrifugation involves the separation of different sized particles by very high centrifugal forces. This technique is fundamental to modern biology and requires a dedicated machine capable of achieving such high forces. Most laboratories in the fields of cell biology and biochemistry use this technique routinely and these machines are in very high demand. Tabletop ultracentrifuges are specifically designed to separate small samples and achieve remarkably high separation forces. We previously had a tabletop ultracentrifuge but this machine was more than 15 years old and is now obsolete. During its last breakdown the service representative indicated that the parts were no longer available for its repair and that it would need to be replaced. Our group of investigators is currently traveling to other buildings to perform ultracentrifugation, but the problem associated with this is not only the travel time and the difficulty booking time on other people's equipment. The major problems are that samples can be degraded if not used promptly after separation, and in some cases the materials that were separated can become remixed during travel. The current application is therefore to seek a replacement for this machine that can be housed in space central to our laboratories.
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会议论文
Regulation of septin polymerization in vitro
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批准号:RGPIN-2020-06143
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.06万
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财政年份:2022
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负责人:Trimble, William
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依托单位:
Regulation of septin polymerization in vitro
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批准号:RGPIN-2020-06143
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.06万
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财政年份:2021
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负责人:Trimble, William
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依托单位:
Regulation of septin polymerization in vitro
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批准号:RGPIN-2020-06143
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.06万
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财政年份:2020
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负责人:Trimble, William
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依托单位:
NSF-mediated disssembly of SNARE complexes
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批准号:RGPIN-2015-05202
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.28万
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财政年份:2019
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负责人:Trimble, William
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依托单位:
NSF-mediated disssembly of SNARE complexes
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批准号:RGPIN-2015-05202
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.28万
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财政年份:2018
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负责人:Trimble, William
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依托单位:
NSF-mediated disssembly of SNARE complexes
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批准号:RGPIN-2015-05202
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.28万
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财政年份:2017
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负责人:Trimble, William
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依托单位:
NSF-mediated disssembly of SNARE complexes
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批准号:RGPIN-2015-05202
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.28万
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财政年份:2016
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负责人:Trimble, William
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依托单位:
NSF-mediated disssembly of SNARE complexes
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批准号:RGPIN-2015-05202
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.28万
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财政年份:2015
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负责人:Trimble, William
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依托单位:
Regulation of membrane fusion
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批准号:121595-2010
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.97万
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财政年份:2014
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负责人:Trimble, William
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依托单位:
Regulation of membrane fusion
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批准号:121595-2010
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.97万
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财政年份:2013
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负责人:Trimble, William
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依托单位:
Regulation of membrane fusion
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批准号:121595-2010
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.97万
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财政年份:2012
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负责人:Trimble, William
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依托单位:
Regulation of membrane fusion
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批准号:121595-2010
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.97万
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财政年份:2011
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负责人:Trimble, William
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依托单位:
Regulation of membrane fusion
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批准号:121595-2010
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.97万
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财政年份:2010
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负责人:Trimble, William
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依托单位:
Regulation of membrane fusion
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批准号:121595-2005
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.59万
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财政年份:2009
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负责人:Trimble, William
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依托单位:
Regulation of membrane fusion
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批准号:121595-2005
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.59万
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财政年份:2008
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负责人:Trimble, William
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依托单位:
Regulation of membrane fusion
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批准号:121595-2005
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.59万
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财政年份:2007
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负责人:Trimble, William
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依托单位:
Regulation of membrane fusion
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批准号:121595-2005
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.59万
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财政年份:2006
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负责人:Trimble, William
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依托单位:
Regulation of membrane fusion
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批准号:121595-2005
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项目类别:Discovery Grants Program - Individual
-
资助金额:$3.59万
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财政年份:2005
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负责人:Trimble, William
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依托单位:
Regulation of membrane fusion
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批准号:121595-2000
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.06万
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财政年份:2004
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负责人:Trimble, William
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依托单位:
Regulation of membrane fusion
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批准号:121595-2000
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项目类别:Discovery Grants Program - Individual
-
资助金额:$3.06万
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财政年份:2003
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负责人:Trimble, William
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依托单位:
海外基金