Strengthening the evidence base for the management of common severe infectious diseases

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There are currently large gaps in the evidence base for management of common severe bacterial infections. My research plan focuses on the most common of these: Staphylococcus aureus infections, bone and joint infections, and severe sepsis. In order to both generate important evidence to inform practice, as well as to develop my own skills and experience as an expert in clinical trials, I have initiated or planned randomised controlled trials in each of these areas.