Structural characterization of a novel AB5 cytoxin - SubAB

新型 AB5 细胞毒素 - SubAB 的结构表征

• 批准号: nhmrc : 519506
• 负责人: Dr Travis Beddoe
• 金额: $ 14.05万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Career Development Fellowships
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2010-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/structural-characterization-novel-cytoxin-subab/115729
• 关键词: Structural; characterization; novel; AB5; cytoxin

The proposed research program, using a combinantion of structural biology and biophysical techniques will provide insight into the role of novel AB5 toxin from E. coli. This study will not only improve our fundamental understanding the mode of action of this toxin from this devastating pathogen, but could lead to the design of rational antimicrobials. The knowledge gained will increase Australian international research profile.

拟议的研究计划，使用结构生物学和生物物理技术的结合，将深入了解来自大肠杆菌的新型AB5毒素的作用。这项研究不仅将提高我们对这种破坏性病原体的毒素作用方式的基本理解，而且可能导致设计合理的抗菌剂。所获得的知识将提高澳大利亚的国际研究形象。