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Structural investigation into the regulation of the colony stimulating factor receptor, c-FMS.

Structural investigation into the regulation of the colony stimulating factor receptor, c-FMS.
集落刺激因子受体 c-FMS 调节的结构研究。
批准号:
nhmrc : 519566
负责人:
Dr Mark Walter
金额:
$19.16万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Early Career Fellowships
财政年份:
2008
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2008-01-01 至 2011-12-31

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中文摘要
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英文摘要
The colony stimulating factor receptor, c-FMS is a member of a family of protein signalling molecules expressed on the cell surface that are implicated in the development of serious diseases in humans, such as inflammatory diseases and cancer. A number of important proteins bind to and regulate c-FMS in different ways. I intend to visualise these interactions to further understand how c-FMS activity is controlled by alternative means.
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Structure and function of the AMP-activated protein kinase gamma subunit
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