Investigating the effects of heterosis and stress on the Zea mays epigenome

研究杂种优势和胁迫对玉米表观基因组的影响

• 批准号: 364379-2008
• 负责人: Lukens, Lewis
• 金额: $ 2.91万
• 依托单位: University of Guelph
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Accelerator Supplements
• 财政年份: 2008
• 资助国家: 加拿大
• 起止时间: 2008-01-01 至 2009-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=406111
• 关键词: Investigating; effects; heterosis; stress; Zea

Genomes can change dynamically. In plants, these changes can occur in response to external stimuli such as water stress. Or, changes can occur in response to hybridization between different individuals. Whole genome sequences and new technologies in molecular and computational biology enable us to investigate these changes on a genome-wide scale. In this project, we will characterize DNA modifications across the maize genome that occur in response to water stress and hybridization. We will determine how transposable elements and small RNAs contribute to these genomic changes. Finally, we will investigate if genome modifications differ across individuals. This research will enhance our understanding of how plant genomes respond to stimuli, the mechanisms of these responses, and the natural diversity of these responses. This knowledge may help enhance the productivity and sustainability of important crop plants.

基因组可以动态变化。在植物中，这些变化可以发生在对外界刺激的反应中，例如水分胁迫。或者，不同个体之间的杂交可能会发生变化。全基因组序列和分子和计算生物学的新技术使我们能够在全基因组范围内研究这些变化。在这个项目中，我们将描述玉米基因组中发生的对水分胁迫和杂交的反应的DNA修饰。我们将确定转座元件和小RNA如何对这些基因组变化做出贡献。最后，我们将调查基因组修改是否因个体而异。这项研究将加深我们对植物基因组对刺激的反应、这些反应的机制以及这些反应的自然多样性的理解。这些知识可能有助于提高重要农作物的生产力和可持续性。