Targeting aldosterone receptors in cerebrovascular disease

靶向脑血管疾病中的醛固酮受体

• 批准号: nhmrc : 1064686
• 负责人: A/Pr Thiruma Arumugam
• 金额: $ 57.19万
• 依托单位: La Trobe University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/targeting-aldosterone-receptors-cerebrovascular-disease/455132
• 关键词: Targeting; aldosterone; receptors; cerebrovascular; disease

Stroke represents a major health (accounting for 6% of all deaths) and economic (costs Australia $2.14 billion per year) burden on society, thus clearly more effective treatments are needed. This project will investigate the role of two substances produced in the body – angiotensin II and aldosterone – in stroke outcome, and whether targeting their receptor(s) may prevent poor outcomes following stroke.

中风是社会的主要健康（占所有死亡的6%）和经济（每年花费澳大利亚21.4亿美元）负担，因此显然需要更有效的治疗。该项目将研究体内产生的两种物质-血管紧张素II和醛固酮-在卒中结局中的作用，以及靶向其受体是否可以预防卒中后的不良结局。