Targeting mechanisms that promote cancer cell survival: genetic and chemical approaches to unravel the molecular mechanisms that drive tumour formation, develop novel molecular and chemical probes, and discover new therapeutics

促进癌细胞存活的靶向机制：通过遗传和化学方法来揭示驱动肿瘤形成的分子机制，开发新的分子和化学探针，并发现新的治疗方法

• 批准号: nhmrc : 1043149
• 负责人: Prof David Huang
• 金额: $ 50.13万
• 依托单位: The Walter and Eliza Hall Institute of Medical Research
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/targeting-mechanisms-promote-new-therapeutics/111550
• 关键词: Targeting; mechanisms; promote; cancer; cell

One in three of us are likely to die from cancers. Groundbreaking research, including those made by Prof Huang, has revealed some of the reasons why cancers arise. An attractive way to transform the poor outcomes for cancer patients is to develop better medicines based on findings made by the basic researchers. Prof Huang leads a team at WEHI, including chemists, focused on developing better drugs that exploit knowledge garnered through such basic research in order to improve cancer treatment.

我们中有三分之一可能死于癌症。包括黄教授在内的开创性研究揭示了癌症产生的一些原因。改变癌症患者不良预后的一个有吸引力的方法是根据基础研究人员的发现开发更好的药物。黄教授在WEHI领导了一个包括化学家在内的团队，专注于开发更好的药物，利用通过这些基础研究获得的知识来改善癌症治疗。