Targeting small RNA technologies

针对小RNA技术

• 批准号: nhmrc : 1062683
• 负责人: Dr Michael Gantier
• 金额: $ 28.9万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/targeting-small-rna-technologies/455012
• 关键词: Targeting; small; RNA; technologies

The exciting field of small RNA research was the subject of the 2006 Nobel Prize in Medicine, and holds great potential in the diagnosis and prognosis of disease such as cancer. Recent clinical studies suggest that drugs inhibiting small RNAs called microRNA present novel therapeutic opportunities. By defining the non-specific effects of such drugs and investigating new avenues for their delivery, this project will secure the safe application of these drugs into the clinic.

令人兴奋的小RNA研究领域是2006年诺贝尔医学奖的主题，在癌症等疾病的诊断和预后方面具有巨大潜力。最近的临床研究表明，抑制小rna（称为microRNA）的药物提供了新的治疗机会。通过确定这些药物的非特异性作用，并研究新的给药途径，该项目将确保这些药物在临床中的安全应用。