Targeting the sympathetic nervous system to reduce the burden of fatty liver disease

针对交感神经系统减轻脂肪肝疾病的负担

• 批准号: nhmrc : 1125799
• 负责人: A/Pr Elisabeth Lambert
• 金额: $ 49.71万
• 依托单位: Baker IDI Heart and Diabetes Institute
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/targeting-sympathetic-nervous-liver-disease/947674
• 关键词: Targeting; sympathetic; nervous; system; reduce

The metabolic syndrome is characterised by abdominal obesity, high blood pressure and an increased risk of diabetes development. It is clear from our own observations that the sympathetic nervous system (SNS) is important in the generation of obesity-related illness and, through its stimulation of the liver, plays an important role in the development of obesity-related liver disease. We will target the SNS in order to reduce the burden of obesity-related liver disease.

代谢综合征的特征是腹型肥胖、高血压和糖尿病风险增加。从我们自己的观察中可以清楚地看到，交感神经系统(SNS)在肥胖相关疾病的发生中起着重要的作用，并通过刺激肝脏在肥胖相关肝病的发展中发挥重要作用。我们将针对SNS，以减轻肥胖相关肝病的负担。