Trajectories between childhood internalising behaviour problems and adolescent depressive symptoms

众所周知，抑郁症状会在青春期急剧加剧。经历过一次抑郁症发作的青少年很可能在成年后经历进一步的精神疾病。通过研究早期出现抑郁症状所涉及的因素和过程，可以推动预防抑郁症的努力。为了促进这样的理解，该项目将分析收集到的数据，部分是通过NHMRC对澳大利亚气质项目(ATP)研究人员的支持。ATP数据将被用来检查与抑郁症状从童年到青春期的发展和进展相关的因素。ATP数据集包括从多个来源(家长、教师和青少年)收集的详细纵向数据，涉及儿童和青少年的气质、行为问题、母子关系、健康、抑郁症状、学习成绩、学校适应、社交技能、同伴关系、育儿实践、压力生活事件和社会人口因素。在1983年在队列中登记的2443名原始样本(4-8个月大)中，1350名青少年应在2000年(17-18岁)完成数据收集。通过对本申请中提出的ATP数据的分析，将开发模型来解释儿童和青春期早期影响青少年抑郁发展和病程的风险和弹性过程，针对不同的青少年亚群。为了实现这一目标，分析将：1.确定从童年内化行为问题到青春期抑郁症状的不同轨迹的群体；2.比较群体，以确定导致从内化行为问题到抑郁症状的进展的因素，同时也确定似乎阻碍这种进展的因素；3.比较群体，以确定与青春期一过性和持续性抑郁症状相关的因素。

Depressive symptoms are known to escalate sharply through the adolescent years. Adolescents who experience an episode of depression are very likely to experience further mental illness as adults. Efforts to prevent depressive illness may be advanced by research delineating the factors and processes implicated in the early emergence of depressive symptoms. To advance such an understanding this project will analyse data collected, in part, through NHMRC support to Australian Temperament Project (ATP) researchers. The ATP data will be used to examine factors associated with the development and progression of depressive symptoms from childhood to adolescence. The ATP data set includes detailed longitudinal data collected from multiple sources (parents, teachers and youth) concerning child and adolescent temperament, behavioural problems, mother-child relations, health, depressive symptoms, school achievement, school adjustment, social skills, peer relationships, parenting practices, stressful life events, and sociodemographic factors. Of an original sample of 2443 enrolled in the cohort in 1983 (aged 4-8 months) a subsample of 1,350 adolescents should complete the data collection due in 2000 (age 17-18). Through the analysis of ATP data proposed in this application, models will be developed to explain the risk and resiliency processes in childhood and early adolescence influencing the development and course of adolescent depression, for different subgroups of adolescents. To achieve this objective, analyses will: 1. identify groups who have differing trajectories from childhood internalising behaviour problems to adolescent depressive symptoms; 2. compare groups to identify factors that contribute to the progression from internalising behaviour problems to depressive symptoms, while also identifying factors which appear to impede such progression and; 3. compare groups to identify factors associated with transient versus persistent depressive symptoms in adolescence.