Transcriptional regulation of hematopoietic commitment

血细胞的形成是一个受到严格调控的过程，为我们理解血液稳态提供了一个重要的模型。扰动导致许多疾病，如白血病。干细胞在许多疾病中的应用正在进行中；然而，要想成功，了解正常的细胞行为是至关重要的。我的目标是提高我们对这些过程的理解，并帮助为未来的研究提供框架，旨在更直接地操纵血细胞功能。

Blood cell formation is a tightly regulated process and provides an important model for our understanding of blood homeostasis. Perturbations result in a number of disorders such as leukaemia. The application of stem cells to many diseases is being pursued; yet, to be successful knowledge of normal cellular behavior is crucial. I aim to improve our understanding of these processes and help to provide the framework for future studies aimed at more directly manipulating blood cell functions.