TSLP and dysregulation of anti-viral immunity in atopic dermatitis
TSLP and dysregulation of anti-viral immunity in atopic dermatitis
批准号:
nhmrc : 509199
负责人:
Prof David Tscharke
金额:
$33.61万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2008
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2008-01-01 至 2010-12-31
中文摘要
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英文摘要
Eczema (atopic dermatitis) is a frequent allergy in Australia. People with eczema can suffer very severe skin infections with some viruses, including the virus that causes cold sores, but we do not know why this happens. A newly discovered protein called TSLP is now known to be made by skin affected by eczema and there is evidence that TSLP may interfere with the way the body fights viruses. We will examine whether TSLP programs the immune system so that it is less able to fight viruses.
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