Evolution and development of the visual system in fish

鱼类视觉系统的进化和发展

• 批准号: 371928-2009
• 负责人: Allison, WilliamTed
• 金额: $ 1.46万
• 依托单位: University of Alberta
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2009
• 资助国家: 加拿大
• 起止时间: 2009-01-01 至 2010-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=435024
• 关键词: Evolution; development; visual; system; fish

A long history of research in the field of Visual Ecology has attempted to understand the evolution of fish vision by comparing fish that live in different environments, or by testing visual system efficiencies with varied backgrounds/stimuli. Here we focus instead on testing hypotheses regarding the adaptive value of characters by altering retinal features through gene knockout, knockdown, mis-expression and transgenesis in zebrafish. We will modify the sensitivity and patterns of photoreceptors in zebrafish and their close relatives. The engineered fish will be tested in paradigms of visual system physiology and behaviour to define their visual abilities. Thus we will integrate data of developmental mechanisms/morphology with recordings of visual sensitivity and acuity. This overall approach will be used to investigate:

视觉生态学领域的研究历史悠久，试图通过比较生活在不同环境中的鱼类，或通过测试不同背景/刺激的视觉系统效率来了解鱼类视觉的进化。在这里，我们专注于测试假设，而不是通过改变视网膜功能，通过基因敲除，敲低，错误表达和转基因在斑马鱼的字符的适应性价值。我们将修改斑马鱼及其近亲的感光器的敏感性和模式。工程鱼将在视觉系统生理学和行为的范例中进行测试，以确定它们的视觉能力。因此，我们将整合发育机制/形态学的数据与视觉灵敏度和敏锐度的记录。这一总体方法将用于调查：