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Robotic Biobank

机器人生物样本库

基本信息

批准号：
379853-2008
负责人：
Behzadipour, Saeed
金额：
$ 1.82万
依托单位：
University of Alberta
依托单位国家：
加拿大
项目类别：
Collaborative Research and Development Grants
财政年份：
2009
资助国家：
加拿大
起止时间：
2009-01-01 至 2010-12-31
项目状态：
已结题

来源：
https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=438015
关键词：
Robotic Biobank

项目摘要

In the proposed project a novel robot will be developed to operate inside a freezer at -80C. It will provide a robotic high throughput solution to biobanking, i.e. storage and retrieval of biological samples for a variety of research projects. Biobanking is of strategic importance to a wide range of research activities in health science from genetic research to the development and evaluation of drugs and treatments. Storage of the biological sample tubes at a very low temperature and providing high frequency access to them at the same time introduces a dilemma to automation technology. These samples are sensitive to temperature fluctuations and therefore it is preferred for any automatic handling solution to be located completely inside the freezer. However, the extreme temperature makes such a solution challenging since many of the available technologies fail in such low temperature. In the proposed project, a novel robot is designed in such a way that all the sensitive parts including the actuators and sensors are stationary located outside the freezer. The mechanical power is transported using a single loop of cable. A coordinated movement of the stationary actuators determine the position of the robot end-effector. This has also significantly reduced the moving mass of the robot facilitating the high accelerations and velocities. It is expected that the robot provide 600 accesses to individual sample tubes per hour.

在拟议的项目中，将开发一种新型机器人，在-80 ℃的冰箱内操作。它将为生物库提供机器人高通量解决方案，即为各种研究项目存储和检索生物样本。生物库对于从遗传研究到药物和治疗方法的开发和评估等健康科学领域的广泛研究活动具有战略重要性。在非常低的温度下储存生物样品管并同时提供对它们的高频率访问给自动化技术带来了困境。这些样品对温度波动很敏感，因此，任何自动处理溶液最好完全位于冰箱内。然而，极端的温度使得这种解决方案具有挑战性，因为许多可用的技术在这样的低温下失败。在所提出的项目中，设计了一种新型机器人，其所有敏感部件（包括致动器和传感器）都固定在冰箱外。机械动力是使用一个单一的电缆回路来传输的。固定致动器的协调运动确定机器人末端执行器的位置。这也显著减少了机器人的移动质量，从而促进了高加速度和速度。预计机器人每小时可提供600次访问单个样品管的机会。