Targeting cell death pathways in parasites

针对寄生虫的细胞死亡途径

• 批准号: DE120101730
• 负责人: A/Prof Erinna Lee
• 金额: --
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Early Career Researcher Award
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-02 至 2014-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DE120101730
• 关键词: Targeting; cell; death; pathways; parasites

Schistosomiasis is a disease caused by parasitic worms. Due to the potential for drug resistance, new drugs are needed. This project aims to identify the components needed for parasite survival based on a cell death pathway in schistosomes. Neutralising the activities of these proteins should cause parasite death, providing a new treatment strategy.

血吸虫病是一种由寄生蠕虫引起的疾病。由于潜在的耐药性，需要新的药物。该项目的目的是确定寄生虫生存所需的组件的基础上的细胞死亡途径在寄生虫体。中和这些蛋白质的活性应该会导致寄生虫死亡，这提供了一种新的治疗策略。