Understanding T cell responses to infectious disease across the lifespan

点击翻译按钮获取中文摘要

The effectiveness of immune responses to infectious diseases and vaccines declines during prolonged infection and is compromised in the very young and elderly. This research aims to better understand the compromise of the immune recognition and control of chronic infections and age-related defects in immunity. Such understanding is crucial to the development of strategies to improve the outcome of infections across the lifespan and the design of vaccines for chronic infections such as HIV.