Digital gel documentations system for comparative immunology group

在这里，我们要求凝胶文件系统的比较免疫学组。比较免疫学或动物免疫过程的研究通常通过免疫基因的表达来衡量。我们研究的许多组成部分涉及可视化DNA片段。DNA与一种染料混合，这种染料非常特异地与DNA结合，当被紫外线照射时，它会发出明亮的红色。因此，可以在UV盒（透照器）上观察条带。这些乐队的照片可以永久保存。我们可以通过与已知标准品进行比较来确定基因片段的大小，或者通过分析条带的密度来确定基因表达的量。我们还可以从凝胶中切除DNA，以恢复基因，研究其在细胞系中的功能。这使我们能够确定动物对疾病生物体的反应。该仪器将支持在该领域工作的所有比较免疫学家和微生物学家。 我们的实验室正在研究鸭子是如何对抗流感病毒的，因为它们被杀死鸡、猪和人类的病毒株感染但没有受到伤害。另一个项目通过研究鱼类的系统来检查用于抗体多样性的基因突变体的调节。

Here we request a Gel documentation system for the Comparative Immunology Group. Comparative immunology, or the study of immune processes in animals is often measured by the expression of immune genes. Many components of our research involve visualizing DNA fragments. DNA is mixed with a dye that binds very specifically to the DNA, which when illuminated by UV light, shines bright red. Thus bands can be visualized on a UV box (transilluminator). Photographs can be taken of these bands for a permanent record. We can determine the size of a gene fragment by comparison with known standards, or the amount of a gene expressed by analyzing the density of the band. We can also excise the DNA from the gel to recover the gene to study its function in cell lines. This allows us to determine the response of an animal to disease organisms. This instrument will support all comparative immunologists and microbiologists working in area. Our lab is studying how ducks fight the flu virus, since they are infected but unharmed by strains that kill chickens, pigs, and humans. Another program examines the regulation of the gene mutator used for antibody diversity, by studying the system in fish.