Accurate 3D digitizer for linking tissue mechanics with imaging

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The MicroScribe MX 3D Digitizer requested in this application will extend the research capabilities of the Colleges of Engineering, Medicine and Kinesiology at the University of Saskatchewan in the areas of imaging, biomechanics, tissue mechanics and tissue engineering. One central goal of multidisciplinary musculoskeletal research conducted at the University of Saskatchewan involves assessing bone and cartilage strength with non-invasive imaging tools. These imaging tools include the Canadian Light Source Synchrotron, micro computed tomography (microCT), peripheral Quantitative CT (pQCT), high resolution pQCT, clinical CT and clinical magnetic resonance imaging (MRI). Imaging techniques have been recently developed to estimate mechanical properties of bone and cartilage. However, it is currently not known how well these imaging techniques estimate mechanical properties. Further, without accurate strength estimations we cannot reliably trust results from computer models--specifically finite element (FE) models--of bone and cartilage. The applied MicroScribe MX digitizer will enable us to accurately compare imaged-derived and experimentally-derived mechanical properties, and thus confirm imaged strength estimates using available imaging tools at the University of Saskatchewan. Using reverse engineering techniques, the MicroScribe MX will also enable us to re-create bone and spinal cord tissues as computer models to aid in the design and fabrication of tissue repairing structures such as scaffolds. The key features of this equipment include: high accuracy, low cost, and portability for use with various imaging tools and permanent instruments located throughout the University of Saskatchewan. This device will support the training of students in a multidisciplinary area involving mechanical and biomedical engineering, kinesiology, and medicine. The MicroScribe MX will help us to: (1) reliably estimate bone and cartilage strength; (2) build computer models that can be used to better understand bone and joint diseases; (3) develop low radiation-dose assessments of bone strength using the Canadian Light Source synchrotron; and (4) build artificial structures (scaffolds) for bone and spinal cord repair.