A conceptually new microwave applicator

全新概念的微波涂抹器

• 批准号: 390674-2010
• 负责人: Organ, Michael
• 金额: $ 10.93万
• 依托单位: York University
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments - Category 1 (<$150,000)
• 财政年份: 2009
• 资助国家: 加拿大
• 起止时间: 2009-01-01 至 2010-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=443261
• 关键词: conceptually; new; microwave; applicator

The proposal is to attain a conceptually-new microwave applicator for use in Microwave-Assisted, Continuous-Flow Organic Synthesis (MACOS), a brand new technology developed in the laboratory of Michael G. Organ at York University in Toronto. The applicator will allow the irradiation of chemical reactions that are flowed through narrow diameter tubes that, in theory, can be of any length necessary to complete the transformation that is being conducted. The tubes being developed by Organ, in conjunction with William J. Pietro, a noted Materials Scientist, are lined with microwave-absorbing material that serve like an antenna to transmit energy to the reaction. In some cases, this has resulted in shortening reaction times literally from days to a matter of seconds! Early-stage MACOS systems are being beta tested in other universities (e.g., the University of Kansas) and in major pharmaceutical companies (e.g., Merck Pharmaceuticals). With the newly designed microwave applicator in hand, the MACOS system will soon be at a stage where it is suitable to engineer into a commercially available system that will be manufactured in Canada for use around the world.

该提案旨在获得一种概念上新的微波施加器，用于微波辅助连续流有机合成（MACOS），这是Michael G.器官在约克大学在多伦多。施加器将允许流过窄直径管的化学反应的辐射，理论上，窄直径管可以具有完成正在进行的转化所需的任何长度。Organ与著名的材料科学家William J. Pietro合作开发的管内衬有微波吸收材料，就像天线一样将能量传输到反应中。在某些情况下，这导致反应时间从几天缩短到几秒钟！早期的MACOS系统正在其他大学进行beta测试（例如，堪萨斯大学）和大型制药公司（例如，Merck Pharmaceuticals）。随着新设计的微波辐射器的在手，MACOS系统将很快处于一个阶段，它适合工程到一个商业上可用的系统，将在加拿大制造，供世界各地使用。