A conceptually new microwave applicator

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The proposal is to attain a conceptually-new microwave applicator for use in Microwave-Assisted, Continuous-Flow Organic Synthesis (MACOS), a brand new technology developed in the laboratory of Michael G. Organ at York University in Toronto. The applicator will allow the irradiation of chemical reactions that are flowed through narrow diameter tubes that, in theory, can be of any length necessary to complete the transformation that is being conducted. The tubes being developed by Organ, in conjunction with William J. Pietro, a noted Materials Scientist, are lined with microwave-absorbing material that serve like an antenna to transmit energy to the reaction. In some cases, this has resulted in shortening reaction times literally from days to a matter of seconds! Early-stage MACOS systems are being beta tested in other universities (e.g., the University of Kansas) and in major pharmaceutical companies (e.g., Merck Pharmaceuticals). With the newly designed microwave applicator in hand, the MACOS system will soon be at a stage where it is suitable to engineer into a commercially available system that will be manufactured in Canada for use around the world.