Using twin and family studies to make genomics relevant to population health

利用双胞胎和家庭研究使基因组学与人口健康相关

• 批准号: nhmrc : GNT1137349
• 负责人: Prof John Hopper
• 金额: $ 87.6万
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/using-twin-family-population-health/1348088
• 关键词: Using; twin; family; studies; make

This Fellowship will make major impacts on health by building on decades of research creating large studies of families, and in particular twins. One aim is to produce a simple web-based tool for women to accurately know their risk of breast cancer based on family history, mammography and genetic markers. This could transform breast and genetic screening across the world. Another is to develop new ways of analysing twin data which resolve which risk factors are causal and relevant to prevention.

这项研究将在数十年的研究基础上，对家庭，特别是双胞胎进行大规模研究，从而对健康产生重大影响。其中一个目标是为女性制作一种简单的网络工具，以根据家族病史、乳房X光检查和遗传标记准确地了解她们患乳腺癌的风险。这可能会改变世界各地的乳房和基因筛查。另一个是开发分析双胞胎数据的新方法，以确定哪些风险因素是原因和与预防相关的。