Venom peptide modulators of pain pathways

疼痛通路的毒液肽调节剂

• 批准号: nhmrc : 569927
• 负责人: Prof David Adams
• 金额: $ 455.98万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Programs
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/venom-peptide-modulators-pain-pathways/77277
• 关键词: Venom; peptide; modulators; pain; pathways

The goal of the proposed Program is to improve treatments forpain, especially persistent pain, which remains a poorly managed global health burden. Our pre-eminent team integrates a unique set of complementary research skills in using peptides derived from venomous invertebrates to dissect the pharmacology of pain pathways in persistent pain states, and develop these novel peptides to the point where they can be considered for pre-clinical development in collaboration with commercial partners.

拟议计划的目标是改善疼痛的治疗，特别是持续性疼痛，这仍然是一个管理不善的全球健康负担。我们杰出的团队整合了一套独特的互补研究技能，使用来自有毒无脊椎动物的肽来剖析持续疼痛状态下疼痛通路的药理学，并开发这些新肽，使其可以考虑与商业合作伙伴合作进行临床前开发。