A vulvar cancer cluster caused by genetic susceptibility: investigating the genetic mechanism.

由遗传易感性引起的外阴癌群：研究遗传机制。

• 批准号: nhmrc : 1060187
• 负责人: A/Pr Jacqueline Boyle
• 金额: $ 76.97万
• 依托单位: Menzies School of Health Research
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/vulvar-cancer-cluster-genetic-mechanism/454805
• 关键词: vulvar; cancer; cluster; caused; genetic

Cancer of the vulva is 70 times more common in young Aboriginal women in Arnhem Land than in other women. Human Papillomavirus (HPV), which also causes cervical cancer, is the usual cause of this cancer; initial investigations have found that HPV is present in these cancers but is not the reason for the excessive incidence. This study will investigate inherited risk factors contributing to the development of this disease in this population.

阿纳姆地区年轻土著妇女的外阴癌发病率是其他妇女的70倍。人乳头瘤病毒（HPV），也会导致宫颈癌，是这种癌症的常见原因;初步调查发现，HPV存在于这些癌症中，但不是发病率过高的原因。本研究将调查导致该人群发生该疾病的遗传风险因素。