Fungal morphogenesis and environmental response

我的研究计划的目标是更好地了解真核生物中影响细胞形状和功能的因素，真核生物是包括人类和真菌在内的复杂生物。真菌对人类和生态的影响既有有益的，也有有害的，从循环利用和生物技术到动植物的致病。为了更好地利用或控制真菌的活动，我们需要更好地了解它们的生长、代谢和对外部因素的反应。真菌与动物相比，细胞类型少，细胞结构简单，生命周期短，然而，动物和真菌的生理和遗传控制从根本上是相似的。在真菌中可以方便快捷地进行实验，其结果可以应用于医学研究。为面包霉菌、尼杜拉曲霉等物种开发的分析和分子遗传工具使丝状真菌成为典型的实验模型系统。

The goal of my research program is to better understand factors affecting cell shape and function in eukaryotes, complex organisms that include both humans and fungi. Fungal impacts on humans and on ecology span beneficial and detrimental effects, ranging from recycling and biotechnology to pathogenesis of animals and plants. To better use or control fungal activities, we need improved knowledge of their growth, metabolism, and responses to external factors. Fungi have few cell types, simple cell structures, and short life cycles compared to animals, nevertheless, animal and fungal physiology and genetic controls are fundamentally similar. Experiments can be done easily and quickly in fungi, and the results can be applied to medical research. Analytical and molecular genetic tools developed for species such as the bread mold, Aspergillus nidulans, make filamentous fungi exemplary experimental model systems.