Fungal morphogenesis and environmental response

我的研究计划的目标是更好地了解影响细胞形状和功能的真核生物，复杂的生物体，包括人类和真菌的因素。真菌对人类和生态的影响包括有益和有害的影响，从循环利用和生物技术到动植物的发病机制。为了更好地利用或控制真菌的活性，我们需要更好地了解它们的生长、代谢和对外部因素的反应。与动物相比，真菌的细胞类型少，细胞结构简单，生命周期短，但动物和真菌的生理和遗传控制在根本上是相似的。在真菌中进行实验容易、快捷，实验结果可应用于医学研究。分析和分子遗传工具开发的物种，如面包霉菌，灰曲霉，使丝状真菌示范性实验模型系统。

The goal of my research program is to better understand factors affecting cell shape and function in eukaryotes, complex organisms that include both humans and fungi. Fungal impacts on humans and on ecology span beneficial and detrimental effects, ranging from recycling and biotechnology to pathogenesis of animals and plants. To better use or control fungal activities, we need improved knowledge of their growth, metabolism, and responses to external factors. Fungi have few cell types, simple cell structures, and short life cycles compared to animals, nevertheless, animal and fungal physiology and genetic controls are fundamentally similar. Experiments can be done easily and quickly in fungi, and the results can be applied to medical research. Analytical and molecular genetic tools developed for species such as the bread mold, Aspergillus nidulans, make filamentous fungi exemplary experimental model systems.