Fungal morphogenesis and environmental response

真菌形态发生和环境响应

• 批准号: 203696-2008
• 负责人: Kaminskyj, Susan
• 金额: $ 2万
• 依托单位: University of Saskatchewan
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=453445
• 关键词: Fungal; morphogenesis; environmental; response

The goal of my research program is to better understand factors affecting cell shape and function in eukaryotes, complex organisms that include both humans and fungi. Fungal impacts on humans and on ecology span beneficial and detrimental effects, ranging from recycling and biotechnology to pathogenesis of animals and plants. To better use or control fungal activities, we need improved knowledge of their growth, metabolism, and responses to external factors. Fungi have few cell types, simple cell structures, and short life cycles compared to animals, nevertheless, animal and fungal physiology and genetic controls are fundamentally similar. Experiments can be done easily and quickly in fungi, and the results can be applied to medical research. Analytical and molecular genetic tools developed for species such as the bread mold, Aspergillus nidulans, make filamentous fungi exemplary experimental model systems.

我的研究计划的目标是更好地了解影响真核生物细胞形状和功能的因素，包括人类和真菌的复杂生物。真菌对人类和生态的影响包括有益和有害的影响，从回收利用和生物技术到动物和植物的致病作用。为了更好地利用或控制真菌活动，我们需要更好地了解它们的生长，代谢和对外部因素的反应。与动物相比，真菌的细胞类型少，细胞结构简单，生命周期短，然而，动物和真菌的生理学和遗传控制基本相似。实验可以在真菌中轻松快速地完成，结果可以应用于医学研究。为诸如面包霉菌、构巢曲霉等物种开发的分析和分子遗传工具使丝状真菌成为示例性实验模型系统。