Heme oxygenase integrates cellular responses to oxygen stress

血红素加氧酶整合细胞对氧应激的反应

• 批准号: DP120103170
• 负责人: Prof Roland Stocker
• 金额: $ 25.73万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-06-01 至 2015-05-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP120103170
• 关键词: Heme; oxygenase; integrates; cellular; responses

A deficiency in the protein heme oxygenase-1 causes severe biological consequences including retarded development, chronic inflammation and increased susceptibility to age-associated diseases. By illuminating how heme oxygenase-1 improves cell function the project will eventually assist in preventing or slowing the serious age-associated disorders.

血红素氧合酶-1蛋白的缺乏会导致严重的生物学后果，包括发育迟缓、慢性炎症和对年龄相关疾病的易感性增加。通过阐明血红素加氧酶-1如何改善细胞功能，该项目最终将有助于预防或减缓严重的年龄相关疾病。