NOX enzymes as mediators of inflammation-triggered neurodegeneration: modulating NOX enzymes as novel therapies
NOX enzymes as mediators of inflammation-triggered neurodegeneration: modulating NOX enzymes as novel therapies
批准号:
nhmrc : 1037879
负责人:
Prof Roland Stocker
金额:
$66.34万
依托单位国家:
澳大利亚
项目类别:
Targeted Calls
财政年份:
2012
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2012-01-01 至 2017-12-31
中文摘要
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英文摘要
The NEURINOX project aims at identifying novel therapeutic targets for neurodegenerative diseases; an increasing health issue for the ageing Australian population. NADPH oxidases (NOX) enzymes, generate reactive oxygen species, and are key regulators of neuroinflammation. Inflammatory dysregulation is characterized by a change in NOX activity. NEURINOX will expound the links between neuroinflammation, NOX enzyme activity & neurodegenerative diseases to identify novel therapeutic targets to treat neuroinflammation.
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Quantifying reactive species in biological systems
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批准号:DP170101453
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财政年份:2017
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负责人:Prof Roland Stocker
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依托单位:
Oxidative Processes in Vascular Health and Disease
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Oxidative Processes in Vascular Health and Disease
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批准号:nhmrc : GNT1111632
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项目类别:Research Fellowships
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资助金额:$85.2万
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财政年份:2016
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依托单位:
How do cells regulate the synthesis and localisation of coenzyme Q?
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批准号:DP150102408
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项目类别:Discovery Projects
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财政年份:2015
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负责人:Prof Roland Stocker
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依托单位:
Heme oxygenase integrates cellular responses to oxygen stress
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批准号:DP120103170
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项目类别:Discovery Projects
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资助金额:$25.73万
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财政年份:2012
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依托单位:
The role of oxidative processes in atherosclerosis and related diseases
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批准号:nhmrc : 1003484
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项目类别:Research Fellowships
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资助金额:$64.42万
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财政年份:2011
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负责人:Prof Roland Stocker
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依托单位:
Oxidative stress bioanalytical facility
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批准号:LE100100125
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项目类别:Linkage Infrastructure, Equipment and Facilities
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资助金额:$22.0万
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财政年份:2010
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负责人:Prof Roland Stocker
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依托单位:
Cellular Responses to Adversity: Oxidative Stress and Protection Against Oxidative Damage
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批准号:DP0988470
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项目类别:Discovery Projects
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资助金额:$21.07万
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财政年份:2009
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负责人:Prof Roland Stocker
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依托单位:
Research Fellowship - Grant ID:401106
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批准号:nhmrc : 401106
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项目类别:NHMRC Research Fellowships
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资助金额:$55.09万
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财政年份:2006
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负责人:Prof Roland Stocker
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依托单位:
Lipoprotein oxidation, antioxidants & atherosclerosis
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批准号:nhmrc : 151602
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项目类别:NHMRC Research Fellowships
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资助金额:$43.46万
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财政年份:2001
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负责人:Prof Roland Stocker
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依托单位:
Lipoprotein oxidation, antioxidants and atherosclerosis
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批准号:nhmrc : 151600
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项目类别:NHMRC Project Grants
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资助金额:$18.79万
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财政年份:2001
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负责人:Prof Roland Stocker
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依托单位:
Video Pro 32 image system
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批准号:nhmrc : 1506
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项目类别:NHMRC Infrastructure Grants
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资助金额:$0.5万
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财政年份:2000
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负责人:Prof Roland Stocker
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依托单位:
REGULATION AND NOVEL FUNCTIONS OF INDOLEAMINE 2,3-DIOXYGENASE
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批准号:nhmrc : 119230
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项目类别:NHMRC Project Grants
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资助金额:$17.9万
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财政年份:2000
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负责人:Prof Roland Stocker
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依托单位:
Mechanism of lipid and protein oxidation of esterified fatty acids by lipoxygenasis
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资助金额:$17.41万
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财政年份:1998
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负责人:Prof Roland Stocker
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依托单位:
Low density lipoprotein oxidation and antitoxidation inatherosclerosis
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批准号:nhmrc : 970998
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项目类别:NHMRC Project Grants
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资助金额:$31.38万
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财政年份:1997
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负责人:Prof Roland Stocker
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依托单位:
海外基金