Replacement of the departmental X-ray diffractometer

更换部门X射线衍射仪

• 批准号: 406768-2011
• 负责人: Morris, Robert
• 金额: $ 10.9万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments - Category 1 (<$150,000)
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=472554
• 关键词: Replacement; departmental; ray; diffractometer

The Departmental X-ray Diffractometer is a Bruker instrument purchased in 1997. Departmental Crystallographer Dr Alan Lough runs this instrument, mounts crystals supplied by 14 research groups in the Department of Chemistry and from other Universities in Canada and around the world and solves their structures, about 300 per year. The mechanical parts of the diffractometer are starting to wear and the detector and software are obsolete. This is a proposal to replace the diffractometer with a modern, more productive and sensitive one in order to increase efficiency and quality of the molecular structures determined. The X-ray source is currently molybdenum. This proposal requests a copper source since there is increased demand to determine the absolute configuration of enantiopure organic compounds targetted to drug and other fine chemical applications.

部门X射线衍射仪是1997年购买的布鲁克仪器。部门晶体学家Alan Lough博士运行该仪器，安装由化学系和加拿大及世界各地其他大学的14个研究小组提供的晶体，并解决其结构，每年约300个。衍射仪的机械部件开始磨损，检测器和软件也已过时。这是一个建议，以取代衍射仪的现代化，更有效和敏感的，以提高效率和质量的分子结构确定。 X射线源目前是钼。该提案要求铜源，因为对确定针对药物和其他精细化学品应用的对映纯有机化合物的绝对构型的需求增加。