Transition metal chemistry and catalysis

过渡金属化学与催化

• 批准号: 1311-2013
• 负责人: Morris, Robert
• 金额: $ 9.03万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2014
• 资助国家: 加拿大
• 起止时间: 2014-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=543955
• 关键词: Transition; metal; chemistry; catalysis

Hydrogenation catalysts are used by industry to produce fuels, bulk chemicals and fine chemicals including pharmaceuticals, agrochemicals and fragrances. They are usually composed of expensive, rare and toxic platinum metals. Since 2007 our group has discovered and invented sustainable and much cheaper iron catalysts that promise to replace some conventional catalysts used for the asymmetric hydrogenation of ketones and imines for the production of valuable alcohols and amines. For example, certain alcohols can be used for the synthesis of drugs used in chemotherapy, and selected amines, in the synthesis of antidepressants and antibiotics. Cheap iron catalysts might also find application in the energy field in the hydrogenation of carbon dioxide as well as hydrogen storage and evolution.

加氢催化剂被工业用于生产燃料、散装化学品和精细化学品，包括药品、农用化学品和香料。它们通常由昂贵、稀有和有毒的铂金属组成。自2007年以来，我们的团队已经发现并发明了可持续和更便宜的铁催化剂，有望取代一些用于酮和亚胺不对称氢化生产有价值的醇和胺的传统催化剂。例如，某些醇可用于合成用于化疗的药物，某些胺可用于合成抗抑郁药和抗生素。廉价的铁催化剂也可能在能源领域的二氧化碳加氢以及氢的储存和释放中找到应用。