Mathematical approaches for controlling emerging and re-emerging diseases

这项建议的目的是设计一个数学模型框架，用于评估针对某些对公共卫生具有重要意义的人类疾病的传播的控制战略，特别是儿童疾病、病媒传播的疾病(例如登革热和疟疾)、性传播疾病(例如艾滋病毒)、呼吸系统疾病(例如季节性和大流行性流感、结核病、SARS)和其他可通过疫苗预防的疾病(例如白喉、肺炎球菌病、轮状病毒、黄热病、伤寒、霍乱)。虽然这些疾病中的许多是可控制和/或可治疗的，但它们仍然是主要的全球威胁。例如，来自世界卫生组织的数据显示，目前全球有近4600万艾滋病毒携带者，到目前为止，该疾病已夺走了2000多万人的生命。

The aim of this proposal is to design a mathematical modelling framework for assessing control strategies against the spread of some classes of human diseases of public health importance, notably childhood diseases, vector-borne diseases (e.g., dengue and malaria), sexually-transmitted diseases (e.g., HIV), respiratory diseases (e.g., seasonal and pandemic influenza, tuberculosis, SARS) and other vaccine-preventable diseases (e.g., diphtheria, pneumococcal disease, rotavirus, yellow fever, typhoid, cholera). Although many of these diseases are controllable and/or treatable, they continue to be major global menace. For instance, figures from the World Health Organization show that nearly 46 million people currently live with HIV globally, and the disease has so far claimed the lives of over 20 million people.