Mathematical approaches for controlling emerging and re-emerging diseases

这一建议的目的是设计一个数学模型框架，以评估控制某些对公共卫生具有重要意义的人类疾病传播的战略，特别是儿童疾病、病媒传播疾病（例如登革热和疟疾）、性传播疾病（例如艾滋病毒）、呼吸道疾病（例如季节性和大流行性流感、结核病、严重急性呼吸系统综合症）和其他疫苗可预防的疾病(例如白喉、肺炎球菌病、轮状病毒、黄热病、伤寒、霍乱)。虽然其中许多疾病是可以控制和/或治疗的，但它们仍然是全球的主要威胁。例如，世界卫生组织的数据显示，目前全球有近4600万人感染艾滋病毒，到目前为止，这种疾病已夺去了2000多万人的生命。

The aim of this proposal is to design a mathematical modelling framework for assessing control strategies against the spread of some classes of human diseases of public health importance, notably childhood diseases, vector-borne diseases (e.g., dengue and malaria), sexually-transmitted diseases (e.g., HIV), respiratory diseases (e.g., seasonal and pandemic influenza, tuberculosis, SARS) and other vaccine-preventable diseases (e.g., diphtheria, pneumococcal disease, rotavirus, yellow fever, typhoid, cholera). Although many of these diseases are controllable and/or treatable, they continue to be major global menace. For instance, figures from the World Health Organization show that nearly 46 million people currently live with HIV globally, and the disease has so far claimed the lives of over 20 million people.