Uterodomes and the evolution of viviparity

子宫穹窿和胎生的进化

• 批准号: ARC : DP0343428
• 负责人: Christopher R Murphy
• 金额: $ 33万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2003
• 资助国家: 澳大利亚
• 起止时间: 2003-01-01 至 2005-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/uterodomes-evolution-viviparity/68286
• 关键词: Uterodomes; evolution; viviparity

Uterodomes and the evolution of viviparity. We will test the hypothesis that uterodomes, which are cell structures unique to the early pregnant uterus in mammals, and the cellular changes accompanying their development, are essential to the evolution of viviparity in amniotes. The proposal stems from our recent discovery that uterodomes develop in the uteri of viviparous lizards as well as in mammals, suggesting key commonalities at the cellular level in the evolution of live birth across amniote vertebrates. We will take advantage of the unique combination of placental types among Australian lizards, including a species with both oviparous and viviparous populations.

子宫顶与胎生的演化。我们将检验这样的假设：子宫体是哺乳动物早期妊娠子宫特有的细胞结构，以及伴随其发育的细胞变化，对于羊水动物胎生的进化至关重要。这一提议源于我们最近的发现，即胎生蜥蜴和哺乳动物的子宫中都有子宫体发育，这表明在胎生脊椎动物活产进化过程中，细胞水平上存在关键的共性。我们将利用澳大利亚蜥蜴中胎盘类型的独特组合，包括一个既有卵生又有胎生种群的物种。