The developmental genetics of major evolutionary transitions: a multidisciplinary investigation of limb reduction and loss in lizards

主要进化转变的发育遗传学：蜥蜴肢体减少和丧失的多学科研究

• 批准号: DP120104365
• 负责人: Prof Michael Lee
• 金额: $ 18.93万
• 依托单位: The University of Adelaide
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP120104365
• 关键词: developmental; genetics; major; evolutionary; transitions

The five-toed limb is an iconic evolutionary innovation of land vertebrates, yet has been lost repeatedly. This project will use anatomical, developmental and genetic approaches to understand how vertebrates lose their legs, whether limbs can be reacquired, and the degeneration of limb genes after they lose their function (analogous to 'vestigial organs').

五趾肢体是陆生脊椎动物的标志性进化创新，但已多次失传。这个项目将使用解剖学、发育学和遗传学的方法来了解脊椎动物是如何失去腿的，肢体是否可以重新获得，以及肢体基因在失去功能后的退化(类似于“退化器官”)。