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Structural and Functional Characterization of Hsp104/ClpB Protein Disaggregating Chaperone Machinery.

Structural and Functional Characterization of Hsp104/ClpB Protein Disaggregating Chaperone Machinery.
Hsp104/ClpB 蛋白解聚伴侣机械的结构和功能表征。
批准号:
242279
负责人:
Rosenzweig Rina
金额:
$9.83万
依托单位:
依托单位国家:
加拿大
项目类别:
Fellowship Programs
财政年份:
2011
资助国家:
加拿大
项目状态:
已结题
起止时间:
2011-10-01 至 2014-10-01

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中文摘要
翻译
一些人类疾病是由蛋白质的错误折叠和有毒蛋白质聚集体的积累引起的。这些疾病包括阿尔茨海默氏症和帕金森氏症,II型糖尿病和海绵状脑病,如克雅氏病。按顺序
英文摘要
Several human diseases are caused by protein misfolding and the accumulation of toxic protein aggregates. These include Alzheimer's and Parkinson's diseases, type II diabetes and the spongiform encephalopathies such as Creutzfeldt-Jakob disease. In order
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