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Palmitoylation in Huntington Disease (Palm HD)

Palmitoylation in Huntington Disease (Palm HD)
亨廷顿病中的棕榈酰化 (Palm HD)
批准号：
174390
负责人：
Hayden Michael R
金额：
$0.0万
依托单位：
University of British Columbia
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2008
资助国家：
加拿大
项目状态：
已结题
起止时间：
2008-10-01 至 2009-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=174390&lang=en
关键词：
Huntington Disease Lipid Modification Palmitoylation Assays And Screens Protein Trafficking Synaptic Function

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中文摘要
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英文摘要
Protein palmitoylation has recently emerged as a dynamic posttranslational modification critical for proper cellular trafficking. Our recent studies show that defects in palmitoylation are associated with dysfunction in Huntington Disease. We will effecti
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Allele-specific lowering of mutant polyQ proteins as treatment for Huntington disease, spinocerebellar ataxia type 3 and spinocerebellar ataxia type 7
Novel Approaches Directed to Prevention and Treatment of Huntington Disease
Canada Research Chair Tier 1
  • 批准号：
    315426
  • 项目类别：
  • 资助金额：
    $101.99万
  • 财政年份：
    2014
  • 负责人：
    Hayden Michael R
  • 依托单位：
    University of British Columbia
Novel approaches to modulate key targets in the pathogenesis of Huntington Disease
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