Palmitoylation in Huntington Disease (Palm HD)
亨廷顿病中的棕榈酰化 (Palm HD)
基本信息
- 批准号:174390
- 负责人:
- 金额:--
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Operating Grants
- 财政年份:2008
- 资助国家:加拿大
- 起止时间:2008-10-01 至 2009-10-01
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Protein palmitoylation has recently emerged as a dynamic posttranslational modification critical for proper cellular trafficking. Our recent studies show that defects in palmitoylation are associated with dysfunction in Huntington Disease. We will effecti
蛋白质棕榈酰化是近年来出现的一种动态的翻译后修饰,对细胞的正常运输至关重要。我们最近的研究表明,棕榈酰化缺陷与亨廷顿病的功能障碍有关。我们将有效地
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Hayden Michael R其他文献
Hayden Michael R的其他文献
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{{ truncateString('Hayden Michael R', 18)}}的其他基金
Allele-specific lowering of mutant polyQ proteins as treatment for Huntington disease, spinocerebellar ataxia type 3 and spinocerebellar ataxia type 7
等位基因特异性降低突变 PolyQ 蛋白作为亨廷顿病、脊髓小脑共济失调 3 型和脊髓小脑共济失调 7 型的治疗
- 批准号:
373043 - 财政年份:2017
- 资助金额:
-- - 项目类别:
Operating Grants
Novel Approaches Directed to Prevention and Treatment of Huntington Disease
预防和治疗亨廷顿病的新方法
- 批准号:
354737 - 财政年份:2016
- 资助金额:
-- - 项目类别:
Operating Grants
Novel approaches to modulate key targets in the pathogenesis of Huntington Disease
调节亨廷顿病发病机制关键靶点的新方法
- 批准号:
268516 - 财政年份:2012
- 资助金额:
-- - 项目类别:
Operating Grants
Novel approaches to modulate key targets in the pathogenesis of Huntington Disease
调节亨廷顿病发病机制关键靶点的新方法
- 批准号:
253299 - 财政年份:2012
- 资助金额:
-- - 项目类别:
Operating Grants
microRNA regulation of ABCA1 and its impact on beta cell function
ABCA1 的 microRNA 调控及其对 β 细胞功能的影响
- 批准号:
252457 - 财政年份:2012
- 资助金额:
-- - 项目类别:
Operating Grants
Drug Safety and Effectiveness Network (DSEN) Pharmacogenomics of Adverse Events National Team(PREVENT)
药物安全性和有效性网络 (DSEN) 不良事件药物基因组学国家小组(预防)
- 批准号:
237872 - 财政年份:2011
- 资助金额:
-- - 项目类别:
Directed Grant
Regulation of Function and Activitiy of ABCA1
ABCA1 功能和活性的调节
- 批准号:
201829 - 财政年份:2010
- 资助金额:
-- - 项目类别:
Operating Grants
CIHR Team in Palmitoylation in Huntington Disease
CIHR 团队在亨廷顿病棕榈酰化方面的研究
- 批准号:
188121 - 财政年份:2009
- 资助金额:
-- - 项目类别:
Operating Grants
Development of Clincial Standards of Care for Huntington Disease Intermediate Allele Predictive Test Results
亨廷顿病中间等位基因预测测试结果临床护理标准的制定
- 批准号:
172289 - 财政年份:2008
- 资助金额:
-- - 项目类别:
Operating Grants
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