Role of Early Childhood Maltreatment and Glucocorticoid Receptor Modulator Gene (FKBP5) in Sensitizing the Biological Stress Response System in Depressed and Non-Depressed Adolescents

早期儿童虐待和糖皮质激素受体调节基因 (FKBP5) 在抑郁和非抑郁青少年生物应激反应系统敏感中的作用

• 批准号: 253285
• 负责人: Mazurka Raegan
• 金额: $ 1.27万
• 依托单位: Queen's University (Kingston, Ontario)
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2012
• 资助国家: 加拿大
• 起止时间: 2012-02-01 至 2013-02-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=253285&lang=en
• 关键词: Adolescence; Childhood Maltreatment; Cortisol; Depression; Fkbp5 Gene; Gene-Environment Interaction; Glucocorticoids; Hpa Axis Reactivity; Stress Sensitization; Trier Social Stress Test

Depression is a debilitating and recurrent illness that affects approximately 11% of Canadians at some point in their lives. Many people experience their first episode of depression as adolescents. Thus, the study of this age group is particularly importa

抑郁症是一种使人衰弱的复发性疾病，在生活中的某个时候影响了大约11%的加拿大人。许多人在青少年时期首次经历抑郁症。因此，对这一年龄组的研究尤为重要。