Computational models of eukaryotic cell polarization/motility
Computational models of eukaryotic cell polarization/motility
批准号:
41870-2012
负责人:
EdelsteinKeshet, Leah
金额:
$5.1万
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2012
资助国家:
加拿大
项目状态:
已结题
起止时间:
2012-01-01 至 2013-12-31
中文摘要
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英文摘要
Cell motility is of fundamental importance in development, immune surveillance, and wound healing in eukaryotes. It also plays a nefarious role in metastasis in cancer. The actin cytoskeleton, which shapes the cell and drives protrusive motility is regulated by layers of signaling pathways. A focal question that motivates my research is how spatio-temporal dynamics of such signaling molecules are coordinated, and how these then combine to produce directed cell motility. My work includes derivation and analysis of mathematical models (both detailed and simplified for analysis), simulations of the time behaviour and spatial distribution of intracellular signaling molecules, and experimental validation (with experimental collaborators).
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会议论文
Models and computation of intracellular signaling in single and collective cell migration
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批准号:RGPIN-2020-04067
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项目类别:Discovery Grants Program - Individual
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资助金额:$5.87万
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财政年份:2022
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负责人:EdelsteinKeshet, Leah
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依托单位:
Models and computation of intracellular signaling in single and collective cell migration
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批准号:RGPIN-2020-04067
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项目类别:Discovery Grants Program - Individual
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资助金额:$5.87万
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财政年份:2021
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负责人:EdelsteinKeshet, Leah
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依托单位:
Models and computation of intracellular signaling in single and collective cell migration
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批准号:RGPIN-2020-04067
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项目类别:Discovery Grants Program - Individual
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资助金额:$5.87万
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财政年份:2020
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负责人:EdelsteinKeshet, Leah
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依托单位:
Computational models of eukaryotic cell polarization/motility
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批准号:41870-2012
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项目类别:Discovery Grants Program - Individual
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资助金额:$5.1万
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财政年份:2019
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负责人:EdelsteinKeshet, Leah
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依托单位:
Computational models of eukaryotic cell polarization/motility
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批准号:41870-2012
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项目类别:Discovery Grants Program - Individual
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资助金额:$5.1万
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财政年份:2018
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负责人:EdelsteinKeshet, Leah
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依托单位:
Computational models of eukaryotic cell polarization/motility
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批准号:41870-2012
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项目类别:Discovery Grants Program - Individual
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资助金额:$5.1万
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财政年份:2017
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负责人:EdelsteinKeshet, Leah
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依托单位:
Computational models of eukaryotic cell polarization/motility
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批准号:41870-2012
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项目类别:Discovery Grants Program - Individual
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资助金额:$5.1万
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财政年份:2016
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负责人:EdelsteinKeshet, Leah
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依托单位:
Computational models of eukaryotic cell polarization/motility
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批准号:41870-2012
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项目类别:Discovery Grants Program - Individual
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资助金额:$5.1万
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财政年份:2015
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负责人:EdelsteinKeshet, Leah
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依托单位:
Computational models of eukaryotic cell polarization/motility
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批准号:41870-2012
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项目类别:Discovery Grants Program - Individual
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资助金额:$5.1万
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财政年份:2014
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负责人:EdelsteinKeshet, Leah
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依托单位:
Computational models of eukaryotic cell polarization/motility
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批准号:41870-2012
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项目类别:Discovery Grants Program - Individual
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资助金额:$5.1万
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财政年份:2013
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负责人:EdelsteinKeshet, Leah
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依托单位:
Mathematical models of actin in cell motility and of swarms/schools in social aggregation
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批准号:41870-2007
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.55万
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财政年份:2011
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负责人:EdelsteinKeshet, Leah
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依托单位:
Mathematical models of actin in cell motility and of swarms/schools in social aggregation
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批准号:349753-2007
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项目类别:Discovery Grants Program - Accelerator Supplements
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资助金额:$1.46万
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财政年份:2010
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负责人:EdelsteinKeshet, Leah
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依托单位:
Mathematical models of actin in cell motility and of swarms/schools in social aggregation
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批准号:41870-2007
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.55万
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财政年份:2010
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负责人:EdelsteinKeshet, Leah
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依托单位:
Mathematical models of actin in cell motility and of swarms/schools in social aggregation
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批准号:349753-2007
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项目类别:Discovery Grants Program - Accelerator Supplements
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资助金额:$4.37万
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财政年份:2009
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负责人:EdelsteinKeshet, Leah
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依托单位:
Mathematical models of actin in cell motility and of swarms/schools in social aggregation
-
批准号:41870-2007
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项目类别:Discovery Grants Program - Individual
-
资助金额:$2.55万
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财政年份:2009
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负责人:EdelsteinKeshet, Leah
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依托单位:
Mathematical models of actin in cell motility and of swarms/schools in social aggregation
-
批准号:41870-2007
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项目类别:Discovery Grants Program - Individual
-
资助金额:$2.55万
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财政年份:2008
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负责人:EdelsteinKeshet, Leah
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依托单位:
Mathematical models of actin in cell motility and of swarms/schools in social aggregation
-
批准号:349753-2007
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项目类别:Discovery Grants Program - Accelerator Supplements
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资助金额:$2.91万
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财政年份:2008
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负责人:EdelsteinKeshet, Leah
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依托单位:
Mathematical models of actin in cell motility and of swarms/schools in social aggregation
-
批准号:41870-2007
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.55万
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财政年份:2007
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负责人:EdelsteinKeshet, Leah
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依托单位:
Mathematical models in biology
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批准号:41870-2002
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.33万
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财政年份:2006
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负责人:EdelsteinKeshet, Leah
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依托单位:
Mathematical models in biology
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批准号:41870-2002
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.33万
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财政年份:2005
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负责人:EdelsteinKeshet, Leah
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依托单位:
国内基金
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