Neuropeptides, synaptic modulation and behavior in arthropods

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Behavior in animals is produced by the central nervous system (CNS) and is strongly influenced by hormones that can act within the CNS, on neuromuscular targets and on visceral organs. The ultimate goal of my research is to understand the mechanisms through which hormones modulate behavior. My research program takes an integrated approach to this problem by studying behavior at the level of whole animals, identifying hormones and neurotransmitters that underlie behavior, and uncovering the mechanisms of action of hormones and transmitters at the cellular and sub-cellular levels. I use invertebrates as model systems for study. Much of my work has focused on "FMRFamide-like peptides", which appear to be present in all animals. These chemicals regulate the heart, vascular tissues, nerve cells, muscle cells and visceral organs.