Regulation of vascular tone in resting and contracting muscles: effects of physical activity

休息和收缩肌肉中血管张力的调节：体力活动的影响

• 批准号: 353634-2008
• 负责人: DeLorey, Darren
• 金额: $ 1.95万
• 依托单位: University of Alberta
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2014
• 资助国家: 加拿大
• 起止时间: 2014-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=549691
• 关键词: Regulation; vascular; tone; resting; contracting

The long-term objective of my research program is to understand the basic physiological mechanisms that regulate blood flow to skeletal muscles at rest and during physiological stress. The maintenance of arterial blood pressure and optimization of skeletal muscle blood flow is dependent upon a dynamic balance between constrictor (that tend to decrease blood flow) and dilator (that tend to increase blood flow) signals that are integrated in the smooth muscle of blood vessels that perfuse skeletal muscles.

我的研究计划的长期目标是了解在休息和生理应激期间调节骨骼肌血流的基本生理机制。 动脉血压的维持和骨骼肌血流量的优化取决于收缩器（趋于减少血流量）和扩张器（趋于增加血流量）信号之间的动态平衡，收缩器和扩张器信号整合在灌注骨骼肌的血管的平滑肌中。